The bacterial pathogen Salmonella Typhi causes typhoid fever, which is a global health problem.
Daniel Humphreys and his team at the Department of Biomedical Science, University of Sheffield, investigate how Salmonella attacks the DNA in human cells to rewire our biology and evade detection by our immune system.
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Additional Information
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Ibler AEM, ElGhazaly M, Naylor KL, Bulgakova NA, F. El-Khamisy S & Humphreys D (2019) Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection. Nature Communications, 10(1). PMID: 31492859
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