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Your brain is constantly receiving signals from the environment via inputs from your five senses. The brain doesn’t simply receive and process them; it takes four complex systems, called the aminergic systems, to process the information and ensure it goes through the correct channels. One of these systems is known as the histaminergic system, which involves a histamine-mediated process. The role of histamine here is one of homeostasis, or balance. It acts as a modulator of the stimuli received relating to
The sleep-wake cycle
Motivation and goal seeking behaviors
Satiety, feeding behaviors and taste perception
Neurotransmitter regulation
Addictive behaviors
Memory formation
Stress
Pain perception
Those all seem pretty important, don’t they; and with this in mind, you can begin to paint a picture of why an increase in your histamine load affects your brain so profoundly.
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Other Conditions associated with Histamine
Sleep disorders
Eating disorders and metabolic syndrome
Neuroinflammation
Migraine
Dementia, Epilepsy and Vestibular disorders16
