CCR5, provides immunity against viruses, especially HIV type.

742.52 Hz CCR5 (C-C Chemokine Receptor Type 5): CCR5 is a gene that encodes a cell surface receptor protein known as C-C chemokine receptor 5. This receptor is primarily found on the surface of white blood cells, particularly T cells and macrophages, and plays a critical role in the immune system's function. One of the most well-known functions of CCR5 is its role as a co-receptor for the entry of the human immunodeficiency virus (HIV) into host cells. HIV uses CCR5, along with CD4, another cell surface receptor, to enter and infect immune cells. Individuals with a genetic mutation that results in the absence of functional CCR5 receptors (CCR5-delta 32 mutation) are highly resistant to HIV infection. Apart from its involvement in HIV infection, CCR5 is also essential for regulating the migration and activation of immune cells in response to chemokine signals. It plays a role in inflammation, immune cell trafficking, and the body's defense against infections. CCR5 has been a target for drug development, with the aim of blocking its interaction with HIV and potentially controlling the virus. Additionally, CCR5 has been implicated in various other diseases and conditions, including autoimmune disorders and certain cancers. Researchers continue to study CCR5 and its interactions to better understand its broader impact on immune responses and human health.

⚠️ A gene may have more than one known or unknown function.
⚠️ A gene can activate or deactivate more than one other gene.
⚠️ Be sure to investigate the effects and characteristics of the relevant Gene.

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