A video that highlights some of the features of ATCC’s organoids.
The scene starts in a simulated brightfield. We see a slow zoom towards the spherically shaped organoids embedded in a gel matrix, represented by the fibers in the background. The camera pans across organoids of various sizes, revealing the uneven texture of their surface.
The camera zeros into one organoid, and a cross section is revealed.
The image switches to immunofluorescence staining of several markers such as CDX2 in blue, ecadherin in red, and CK20 in green. The camera zooms in further to identify Ki67 in pink and MUC5AC in yellow.
The camera zooms in again to a cross section of the plasma membrane. Here we see tumor antigens such as PD-L1 and PD-l2 on the top, underneath we see intracellular signaling molecules such as RAS, FYN, SRC, PTEN, and others.
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