I review the basics of the antibiotic protocol that I intend on taking, once my mast cell activation is better controlled. I intend on taking this protocol based on the expertise of my two Bartonella literate medical doctors and my own anecdotal experience. I then address some common questions about this protocol.

✩ WAYS TO SUPPORT MY HARD WORK
I believe that everyone should have access to affordable, high-quality healthcare and I also believe that people should be compensated for their hard work. If you appreciate my hard work, research, and advocacy, you can also support me in the following ways:
→ PayPal: username @bartonellababe or search Jake Picker
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✩ No one needs to support me in this way and please do not gift me if you are not in a position to do so!
→ SHOP MY MERCH HERE: [ Ссылка ]
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✩ Thank you for supporting my hard work and my channel! See more ways to support my channel below.

✩ 25% of all MERCH proceeds go to the Bartonella Project at the North Carolina State University College of Veterinary Medicine. Link to donate directly to the Bartonella Project:
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✩Instagram: @bartonella_babe
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✩Inquiries: jakethebartonellababe@gmail.com

JOIN our bartonellosis support group on Facebook called BREAKING DOWN BARTONELLA:
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Time stamps:
0:00 Intro
1:32 Basics of the antibiotic protocol
5:02 Why did I choose this protocol?
7:43 My experience with this protocol
11:23 Why use clarithromycin over azithromycin?
13:35 CYP3A4 pathway introduction
14:25 Interactions between clarithromycin and the rifamycins
14:37 CYP3A4, cortisol, hormones, and prescription drugs
15:27 Interactions between clarithromycin and rifampin
16:26 Interactions between clarithromycin and rifabutin
16:54 Neutropenia and raised liver enzymes (ALT, AST)
18:16 Uveitis
19:45 Why use hydrocortisone? Aren't steroids bad to use with infections?
21:17 How and when should I take my antibiotics?
21:47 Why not doxycycline or other antibiotics?
22:49 This protocol seems too long/aggressive
24:27 Future videos on treatment

Videos referenced:
Galaxy's webinar with Dr. Mozayeni (and Dr. Breitschwerdt): [ Ссылка ]
Jack and Amy's bartonellosis success story!: [ Ссылка ]

Studies referenced:
1. Biswas, S., Maggi, R. G., Papich, M. G., & Breitschwerdt, E. B. (2010). Molecular mechanisms of Bartonella henselae resistance to azithromycin, pradofloxacin and enrofloxacin. Journal of antimicrobial chemotherapy, 65(3), 581-582.
2. Kazama, I., Saito, K., Baba, A., Mori, T., Abe, N., Endo, Y., ... & Yamauchi, M. (2016). Clarithromycin dose-dependently stabilizes rat peritoneal mast cells. Chemotherapy, 61(6), 295-303.
3. McDonnell, A. M., & Dang, C. H. (2013). Basic review of the cytochrome p450 system. Journal of the advanced practitioner in oncology, 4(4), 263.
4. Wallace Jr, R. J., Brown, B. A., Griffith, D. E., Girard, W., & Tanaka, K. (1995). Reduced serum levels of clarithromycin in patients treated with multi-drug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection. Journal of Infectious Diseases, 171(3), 747-750.
5. Hafner, R., Bethel, J., Power, M., Landry, B., Banach, M., Mole, L., ... & Cohn, D. (1998). Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers. Antimicrobial agents and chemotherapy, 42(3), 631-639.
6. Griffith, D. E., Brown, B. A., Girard, W. M., & Wallace Jr, R. J. (1995). Adverse events associated with high-dose rifabutin in macrolide-containing regimens for the treatment of Mycobacterium avium complex lung disease. Clinical infectious diseases, 21(3), 594-598.
7. Aronson, J. K. (Ed.). (2015). Meyler's side effects of drugs: the international encyclopedia of adverse drug reactions and interactions. Elsevier.
8. Crabol, Y., Catherinot, E., Veziris, N., Jullien, V., & Lortholary, O. (2016). Rifabutin: where do we stand in 2016?. Journal of Antimicrobial Chemotherapy, 71(7), 1759-1771.
9. Zimran, E., Shilo, S., Florescu, T., Dotan, S., Balag, S., Mevorach, D., ... & Amer, R. (2012). Paradoxical response in ocular bartonellosis. Journal of ophthalmic inflammation and infection, 2(1), 53-56.

Best diagnostic testing:
www.galaxydx.com

Dr. B. Robert Mozayeni's research use only confocal laser scanning microscope with fluorescent tags for Bartonella henselae:
[ Ссылка ]

#Bartonellosis #Bartonella #Bartonellatreatment #BartonellaBabe

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