Parasympathomimetics: Clinical Uses & Classification of Direct-Acting Cholinergic Drugs
In this video, we'll discuss parasympathomimetics, drugs that act on the cholinergic system. We'll also be classifying the various direct-acting cholinergic drugs and discussing their clinical uses.
If you're interested in cholinergic drugs and their clinical uses, then this video is for you! By the end of this video, you'll know everything you need to know about parasympathomimetics and direct-acting cholinergic drugs.
In this video, we have discussed the clinical uses and classification of parasympathomimetics, also known as cholinergic agonists. These agents bind to muscarinic receptors or nicotinic receptors and show their action. This video includes explicitly direct-acting cholinergic agonists clinical uses. While the indirect-acting agonists will be covered in the next video.
Cholinergic agonists are divided into direct-acting agonists and indirect-acting agonists. The direct-acting agonists are further divided into cholinesterase, which includes agents like acetylcholine, bethanechol, methacholine, etc., and alkaloids, including nicotine, muscarine, and pilocarpine. Their clinical uses mostly contain xerostomia or dry mouth, lack of tears, glaucoma, myasthenia gravis, Sjogren syndrome, GIT peristalsis problems, urine obstruction, etc.
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COVERED TOPICS
PARASYMPATHOMIMETICS
1. Classification
1.2. Indirect-acting agonists
1.2.1 Reversible agonists
edrophonium
physostigmine
pyridostigmine
rivastigmine
ambenonium
tacrine
donepezil
1.2.2. Irreversible agonists
organophosphate compounds
echothiophate
Insecticide parathion and malathion
nerve gases
soman
sarin
LINKS:
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