At Ending Age-Related Diseases, John Lewis of Oisin Biotechnologies discussed senolytics, which are drugs that kill senescent cells. He explained the differences between healthy and senescent cells along with the senescence-associated secretory phenotype (SASP) responsible for systemic inflammation. He went into detail about senolytics and what his company looks for when creating them, including details about suicide genes and biomarkers of senescence. He also discussed issues with bringing these drugs to humans and suggested oncology as a possible method for bringing them to the clinic.
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John Lewis | Senolytics
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gerontologylongevitylifespanLife Extension Advocacy FoundationLEAFEnding Age-Related DiseasesXPRIZErejuvenationrejuvenation biotechnologyresearchbiotechnologylife extensionconferenceinvestmentinvestorsresearchersAgingAgeingHealth CareHealthspanCooper UnionNew York CityNYCOisin Biotechnologiessenolyticssenescent cellscellular senescenceSASPbiomarkersgeneticsapoptosisoncology