The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system where neurons reside.

It is theoretical that Since the BBB regulates the transport of insulin into the brain and by extension, helps to regulate CNS levels, so it may be possible that BBB response to insulin and alterations or damage in BBB function could impact CNS insulin resistance.

damage to the BBB system has been implicated in a lot of brain and body disorders including, multiple sclerosis, stroke, and epilepsy.
the field here will attempt to induce and push for the generation of specialized brain capillary endothelial cells targeted to damaged/depleted areas to help facilitate a faster repair.

2-3 times until desired results.

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