Diabetes mellitus causes both microvascular and macrovascular complications. Microvascular complications, caused by the damage of small blood vessels, includes nephropathy (kidney disease), retinopathy (eye damage) and neuropathy (nerve damage) whereas macrovascular complication, caused by the damage of large blood vessels, includes blood vessels arteries and veins. There are six metabolic pathways are there which normally leads to these complications. These pathways are sorbitol pathway, advanced glycation pathway, Hexosamine pathway, PKC pathway, ketoaldehyde pathway and oxidative stress.
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Diabetic Complications #pkprabhakar #clinicalbiochemistry
Теги
sorbitol pathwayHexosamine pathwayPKC pathwayadvance glyacated end product pathwayoxidative phosphorylationenediol pathwaymicrovascular complicationsmacrovascular complicationscardiovascular diseasestype 2blood sugartype 2 diabetesretinopathy diabeticretinopathy treatmentretinopathy of prematuritynephropathy diabeticnephropathy kidney diseasenephropathy pronunciationmicrovascular complications of diabetesneuropathy symptoms
