Autophagy is the body's way of cleaning out damaged cells, in order to regenerate newer, healthier cells. “Auto” means self and “phagy” means eat. So the literal meaning of autophagy is “self-eating.” Resveratrol is a natural polyphenol, released by certain plants in response to attack or injury. The compound is found in a number of foods, including grapes, blueberries, raspberries, red wine, and dark chocolate. Resveratrol-induced autophagy has been suggested to be a key process in mediating many beneficial effects of resveratrol. Scientists found that long-term resveratrol treatment of individuals with mild to moderate Alzheimer's appeared to stop, or slow the progress of the disease.
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David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.
Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.
Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.
He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time's Top 50 in healthcare in 2018.
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DISCLAIMER: Please note that none of the information in this video constitutes health advice or should be substituted in lieu of professional guidance. The video content is purely for informational purposes.
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