Correction for 9:15 - I meant to say non-polar.
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In this video I am following a method which uses asymmetric organocatalysis with the catalyst L-Proline. This method (from 2022) is a prime example of how the discovery of organocatalysis in 2000 is still used today and how the 2021 nobel prize shined a light on it. In the procedure, a bicyclic enal is synthesized, which is a key intermediate for the synthesis of several relevant hormones in medicine.
Procedure:
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![](https://i.ytimg.com/vi/WcyTdXxQxBM/maxresdefault.jpg)