Macrophages populate most organs and remove dead cells. Although few cells die in healthy hearts, Nicolas-Avila et al. show that macrophages continuously phagocytose small particles loaded with mitochondria that are ejected from cardiomyocytes, the beating cells of the heart. The process facilitates mitochondria turnover, prevents inflammation, and preserves cardiac fitness. Check out the paper at: [ Ссылка ]31073-4.
J.A. Nicolás-Ávila, A.V. Lechuga-Vieco, L. Esteban-Martínez, M. Sánchez-Díaz, E. Díaz-García, D.J. Santiago, A. Rubio-Ponce, J.L. Li, A. Balachander, J.A. Quintana, et al. (2020). A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart. Cell 183.
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