Nadeem Bilani, MD, Icahn School of Medicine at Mount Sinai, New York, NY, provides an overview of survival outcomes in premenopausal patients with HR+/HER2- breast cancer and lymph node micro-metastasis. There is no consensus on the treatment strategy for patients with micro-metastasis, despite chemotherapy being recommended in patients with 1-3 lymph nodes. Evaluation of data from the National Cancer Database (NCDB) revealed that whilst addition of chemotherapy to endocrine therapy was beneficial in patients with a recurrence score of less than 26 involving 1-3 lymph nodes, patients with micro-metastatic disease had no survival advantage. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Annual Congress in Chicago, IL.
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