In the late 1950s, a new drug called thalidomide hit the market with promises to be a safe treatment for morning sickness in pregnant women. However, reports soon started emerging of babies being born with horrifying birth defects, missing or flipper-like limbs. Doctors were baffled - what could have possibly caused these abnormalities?
01:21 The Hunt for Answers: Investigating the Thalidomide Crisis.
02:50 Unraveling the Mystery: The Phocomelia Epidemic and the Search for Answers.
04:35 From Wonder to Woe: The Rise and Fall of Thalidomide.
06:28 McBride's Discovery: Unraveling Thalidomide's Secrets.
08:01 Cracking the Code: Hiromitsu's Discovery of Thalidomide's Achilles' Heel.
09:42 Lessons Learned: The Thalidomide Disaster and the Evolution of Drug Safety
11:08 Seeking Truth, Ensuring Safety.
References:
Smithells, R., & Newman, C. (1992). Recognition of thalidomide defects.. Journal of Medical Genetics, 29, 716 - 723.
Silverman, W. (2002). The schizophrenic career of a "monster drug".. Pediatrics, 110 2 Pt 1, 404-6
Taussig, H. (1962). Thalidomide and phocomelia.. Pediatrics, 30, 654-9 .
Lader, M. (1974). ESSAY REVIEW: Thalidomide and the Power of the Drug Companies.. British Journal of Psychiatry, 124, 498 - 499.
Taussig, H. (1962). THALIDOMIDE AND PHOCOMELIA. Pediatrics.
Ridings, J. (2013). The thalidomide disaster, lessons from the past.. Methods in molecular biology, 947, 575-86 .
Randall, T. (1990). Thalidomide has 37-year history.. JAMA, 263 11, 1474 .
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