Does Wellbutrin make anxiety worse? We'll also explore its role in treating anxiety disorders, specifically looking at Bupropion and anxiety.
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Does Wellbutrin Make Anxiety Worse? The video discusses the effects of Wellbutrin for Anxiety Disorders and anxious depression. It challenges the common belief that bupropion worsens anxiety, as this notion is an oversimplification of the complex relationship between neurotransmitters and mental health conditions.

The video cites a meta-analysis of 10 studies that found no significant difference between bupropion and SSRIs (selective serotonin reuptake inhibitors) in treating non-anxious depression. In cases of anxious depression, SSRIs showed a slight advantage over bupropion, but the clinical relevance of this difference was minimal. Bupropion and anxiety has been a question for a while.

For generalized anxiety disorder, a small study suggested no differences between bupropion and Lexapro. Preliminary evidence also indicates that bupropion may be effective in treating social anxiety disorder, but larger studies are needed.

The video acknowledges that a small subset of patients may experience treatment-emergent anxiety with bupropion or SSRIs, but the rates are comparable. It suggests starting with a low dose of bupropion and slowly titrating up to minimize anxiety side effects.

In conclusion, while SSRIs may have a slight edge in treating anxiety disorders, bupropion should not be dismissed as a viable option, particularly for patients concerned about SSRI side effects.

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#depression #bupropion #psychopharmacology

Chapters:
00:00 Psychos Will Farm
00:09 Bupropion & Anxiety
00:34 Why do we assume Wellbutrin is bad for anxiety?
04:00 What is anxiety?
06:33 Anxious Depression (Bupropion effect)
08:40 Generalized Anxiety Disorder
10:12 Social Anxiety Disorder, OCD, Panic
12:30 Summary
14:36 Dosing: Low and Slow
15:51 Outro

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