We already know that Academy Award nominee John C. Reilly is a fantastic actor and one with some serious range - maybe even more than he's given credit for - and that's on display full force in the adaptation of the Patrick DeWitt novel The Sisters Brothers, but the film also marks another major achievement for Reilly; this is his first go producing a feature film.

Reilly, along with his wife and producing partner, Alison Dickey, got ahold of the material and spent years trying to make the film adaptation happen. The dedication and passion paid off because now we have the Jacques Audiard-directed The Sisters Brothers starring Reilly alongside Joaquin Phoenix as Charlie and Eli Sisters, two brothers working as assassins in 1851 in the American West.

The Sisters Brothers opens in select theaters on September 21st, followed by an expansion.

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