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Epinephrine, commonly known as Adrenaline, is a drug that narrows blood vessels and opens airways in the lungs. These effects can reverse severe low blood pressure. Epinephrine is used in Cardiac arrest arrhythmias such as VF, pulseless VT, Asystole, and PEA. It can also be used in symptomatic bradycardia. In addition, Epinephrine is an effective treatment for Anaphylaxis. Epinephrine is available in 1:10,000 or 1:1,000 concentrations. For cardiac arrest, Epinephrine should be delivered IV/IO at 1 mg which is 10 ML of 1:10,000 solution administered every 3 to 5 minutes during resuscitation. For treatment of anaphylactic shock, Epinephrine 1:1,000 is given to a 30 kg or greater patient: 0.3 mg IM or subcutaneously.
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