Now, for this weeks video, i seemed to have set myself an essay question... "Is Aging the price we pay for cancer protection?"... but i thought it would be interesting to explore this topic. Part of the reason I got onto this stemmed from a chapter in a book i recently finished reading all about p53, so cheeky spoiler, that protein may be relevant.
#aging #p53 #cancer
Timestamps;
Intro - 00:00
Why it is the price - 01:18
Why it isn't - 06:42
Summary - 10:00
References;
Antagonistic pleiotropy and p53 EricaUngewitter HeidiScrable
[ Ссылка ]
The Hallmarks of Aging
Cell. 2013 Jun 6; 153(6): 1194–1217.
doi: 10.1016/j.cell.2013.05.039
The Genetics of Aging: A Vertebrate Perspective
[ Ссылка ]
Baker, D., Wijshake, T., Tchkonia, T. et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479, 232–236 (2011). [ Ссылка ]
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