CRISPR-Cas9 genome editing has low efficiency and DSB can result in unwanted indels within a target DNA which can be problematic
To overcome this issue, CRISPR-Cas-based genome editing tools...that is base editors have been developed
There are two types of DNA base editors: Cytosine Base Editor (CBE) and Adenine Base Editor (ABE)
Cytosine Base Editor (CBE) coverts Cytosine (C) to Uridine (U) within target DNA.
