Dr. Herman explains how changing certain lifestyle factors can help reverse CLI.

When someone develops CLI, it's really more of an end-stage type of disease. However, patients who develop rest pain or patients who develop wounds are treated successfully by improving the blood flow towards the lower extremities. They can improve their lifestyle and the overall disease process by stopping smoking, as well as changing their diet or keeping a tight control on their glucose (if one suffers from diabetes).

Specifically, the hemoglobin A1C levels, which is really a manifestation overall of one's metabolic component over the past several months, is a very key indicator in patients to continue to keep those vessels open. It’s what we call “to maintain patency” or to help in healing those wounds. In fact, once somebody does have this diagnosis, although it is the end stage, we really can alter the disease process with lifestyle changes as well as medication and having the patient stop smoking.

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