Watch the Full Video at [ Ссылка ].

MRI-guided Disruption of the Blood-brain Barrier using Transcranial Focused Ultrasound in a Rat Model - a 2 minute Preview of the Experimental Protocol

Meaghan A. O'Reilly, Adam C. Waspe, Rajiv Chopra, Kullervo Hynynen
Sunnybrook Research Institute, Imaging Research; University of Toronto, Department of Medical Biophysics; University of Toronto, Department of Medical Biophysics, and Institute of Biomaterials & Biomedical Engineering (IBBME);

Microbubble-mediated focused ultrasound disruption of the blood-brain barrier (BBB) is a promising technique for non-invasive targeted drug delivery in the brain1-3. This protocol outlines the experimental procedure for MRI-guided transcranial BBB disruption in a rat model.

Visit [ Ссылка ] to explore our entire library of 14,000+ videos of laboratory methods and science concepts.

JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching.

Subscribe to our channel: [ Ссылка ]

свернуть