Dr. Jason Cole is a successful neurosurgeon with a secret. Every night at 8:25 p.m., and lasting exactly 12 hours, Cole is switched into an alternate, evil personality named Ian Price. Cole has been able to suppress Price by injecting a strong pharmaceutical mixture that sedates their shared body, rendering it impossible for the evil alter-ego to function. But one night Cole discovers that their body has grown immune to the drug and Price has emerged in a rage. Angry at having been suppressed, Cole's alternate personality is focused on wreaking havoc on Cole's life, creating problems which could cost him his life, romance and career.

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