In this video Dr Mayank Agrawal is talking about antidepressant medicines.

antidepressant pharmacology

antidepressants
antidepressant
antidepressant drugs
antidepressants side effects
antidepressants classification
antidepressants

Selective serotonin reuptake inhibitors (SSRIs)


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Antidepressant drugs are medications primarily used to treat depressive disorders, such as major depressive disorder, anxiety disorder, obsessive compulsive disorder. dysthymia, and seasonal affective disorder. They work by balancing certain chemicals in the brain, known as neurotransmitters, which are responsible for regulating mood.

There are several different classes of antidepressant drugs, each with its own mechanism of action. Here are some commonly prescribed classes of antidepressants:

1. Selective serotonin reuptake inhibitors (SSRIs): SSRIs are the most commonly prescribed antidepressants. They work by blocking the reabsorption (reuptake) of serotonin, a neurotransmitter that regulates mood. Examples include fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro).

2. Serotonin-norepinephrine reuptake inhibitors (SNRIs): SNRIs increase the levels of both serotonin and norepinephrine in the brain. Examples include venlafaxine (Effexor) and duloxetine (Cymbalta).

3. Tricyclic antidepressants (TCAs): TCAs are an older class of antidepressants that affect the reuptake of multiple neurotransmitters, including serotonin and norepinephrine. They are generally used when other antidepressants have not been effective. Examples include amitriptyline and nortriptyline.

4. Monoamine oxidase inhibitors (MAOIs): MAOIs are an older class of antidepressants that work by blocking the enzyme monoamine oxidase, which breaks down neurotransmitters like serotonin, norepinephrine, and dopamine. They are usually reserved for cases that do not respond to other medications due to potentially serious side effects. Examples include phenelzine (Nardil) and tranylcypromine (Parnate).

5. Atypical antidepressants: This category includes various antidepressants that don't fit into the other classes. Examples include bupropion (Wellbutrin), mirtazapine (Remeron), and trazodone (Desyrel).

It's important to note that antidepressant medications may have different effects on different individuals, and the choice of antidepressant and dosage should be determined by a healthcare professional based on an individual's specific symptoms and medical history. Additionally, antidepressant drugs may have side effects, and it may take several weeks before their full therapeutic effects are noticed. Regular monitoring and open communication with a mental health specialist are crucial when starting or adjusting antidepressant medication.

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