During vertebrate development, cells migrate collectively, often over long distances and taking incredibly stereotypical routes, to produce the final body plan with organs and tissues in the right place.
In their recent paper in Development, Jared Talbot, Sharon Amacher and colleagues from The Ohio State University, the Australian Regenerative Medicine Institute and EMBL Australia mapped the long-distance migration of muscle precursor cells with unprecedented resolution using live imaging. They further identify the Six family genes in a conserved muscle precursor motility pathway.
The movies above show some of the beautiful cell dynamics that occur during muscle precursor cell movements.
Check out the full paper here:
[ Ссылка ]
