Professor Jayashri Kulkarni became a Fellow of the Royal Australian and New Zealand College of Psychiatrists in 1989. As the first Associate Professor/Director of Psychiatry to Dandenong Hospital in 1994, she founded and directed the Dandenong Psychiatry Research Centre (DPRC) and the Monash University Research Centre for Women's Mental Health. She was Director of Psychiatry of Dandenong Area Mental Health Service (DAMHS) for  eight years and directs a large psychiatric research group in her current appointment as Professor of Psychiatry, The Alfred and Monash University.

Take-Home Points

• Depression rates increase dramatically by 16-fold in the 42-52 year age group according to the Harvard Mood Study.

• CNS changes occur 5 years before hot flushes and amenorrhoea between the ages of 43-55 years.

• It is better to start with hormonal treatments such as HRT before antidepressants due to the non-withdrawal aspect.

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