Stage 3B is also called Hormonal Axis Imbalance. The common symptoms include insomnia, myalgia, weight gain, joint pain, exercise intolerance, brain fog, sugar intolerance, baby borderline diabetes, dry skin, feeling cold, slow metabolism, inability to lose weight, PMS, endometriosis, irregular menstrual cycle, fiber cystic breast disease, anxiety, depression, and accumulation of fat at the waistline.
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- Remember that the whole stage 3 itself is called adrenal exhaustion and has 4 phases, and stage 3A is usually characterized by HA axis dysreguation, while stage 3B we're starting to see a hormonal Axis imbalance which we're going to go into more now.
- There are upstream axes, which includes the HPA axis, hypothalamic-pituitary axis that modulates the adrenal cortex function in terms of steroidal hormone synthesis. There's also the HPG or hypothalamic pituitary gonadal hormonal axis which governs the female's ovarian and menstrual cycle. One axis that is seldom looked at is the OAT axis. Now remember the HPA as well as the HPG axis are what we call upstream axes in the sense that they connect the brain , which is the hypothalamus, to the endocrine organs. Now the OAT axis governs the function between the ovarian system, the adrenal system, as well as the thyroid, so that's why it's called the OAT axis as you can see here.
- The ovarian system, the adrenal system, and the thyroid system are well-balanced. They are like a three-legged stool, and you cannot really sit safely on this stool unless all 3 are in good balance. Now the problem clinically is what we see when you have an ovarian adrenal thyroid axis imbalance because you see the symptoms are really convoluted because they represent dysfunction of all 3 groups and they can be quite misleading.
- The common symptoms include insomnia, myalgia, weight gain, joint pain, exercise intolerance, brain fog, sugar intolerance, baby borderline diabetes, dry skin, feeling cold, slow metabolism, inability to lose weight, PMS, endometriosis, irregular menstrual cycle, fiber cystic breast disease, anxiety, depression, and accumulation of fat at the waistline.
- All the PMS and endometriosis symptoms represent estrogen type problems that are tied into the ovarian system. The dry skin and the low metabolism are tied into the thyroid, and the rest ties into the adrenal system. That is very important. You have to understand, is that even for a woman that has had her ovaries removed, they can still have the OAT axis imbalanced because estrogen production and modulations are involved not only in the ovaries, but also at other places including the adrenal glands as well as the fat cells on the adipose tissues where estrogen is produced. So, therefore those who have stress as well as overweight are particularly vulnerable to estrogen dominance even though they may have a complete hysterectomy for whatever issues they had before.
- First, the body's hormonal organs are tied closely together through various axes. The lesser-known OAT axis, as well as the better known HPA axis regulates the stress system. Number 2, when the OAT axis is disrupted, there's an imbalance of hormones that leads to symptoms of estrogen dominance, low-energy - which is adrenal involvement, as well as hypothyroidism. Number 3, each portion of the OAT axis affects the other imbalances of one versus the other and vice versa. Such as estrogen dominance will worsen adrenal function,
which in turn, will aggravate estrogen dominance.
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