Many trials have assess the effectiveness and safety of direct oral anticoaglants. (DOACs) vs Warfarin. In this video, AJM Editor-in Chief Joseph S. Alpert, MD, discusses new a new study of healthcare data from several countries. This new research shows that DOACs and Warfarin are equally effective and safe, as long as the Warfarin is well-monitored and regulated. You can read "Effectiveness and Safety of Direct Oral Anticoagulants Among Octogenarians with Venous Thromboembolism: An International Multidabase Cohort Study" by Douros et al in the January 2023 issue of The American Journal of Medicine on our website amjmed.com.

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