Dr. Michael Silber, a Professor of Neurology at Mayo Clinic College of Medicine and Science in Rochester, MN, assures Clinicians in his article appearing in the January 2018 issue of Mayo Clinic Proceedings, of the efficacy and reasonable safety of opioid usage in patients with restless legs syndrome when standard treatments are ineffective or result in unacceptable adverse effects. Significant improvements in their quality of life can be achieved with low-dose opioid therapy administered with a carefully planned protocol. Available at: [ Ссылка ]

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