The Infinium Methylation Assay from Illumina involves the Infinium platform that uses 'BeadChip' technology to generate a comprehensive genome-wide profiling of human DNA methylation.
Similar to bisulfite sequencing and pyrosequencing, this method quantifies methylation levels at various loci within the genome
The Infinium Methylation Assay detects cytosine methylation at CpG islands based on highly multiplexed genotyping of bisulfite-converted genomic DNA.
Upon treatment with bisulfite, unmethylated cytosine bases are converted to uracil, while methylated cytosine bases remain unchanged.
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