The complete course of events in a virus infected cell is called the infectious cycle. In this lecture we discuss the different phases of the infectious cycle and methods for studying it, including plaque assay, multiplicity of infection, and the particle-to-pfu ratio. Physical methods for detecting viruses include hemagglutination, serological techniques, polymerase chain reaction, and high-throughput sequencing. These methods were used to identify in early 2020 the pandemic coronavirus SARS-CoV-2.

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I’m Vincent Racaniello, Earth’s Virology Professor.

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