Wilson decides to stop further treatment and die with dignity. But House doesn't want him to stop without a fight.

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Season 8 Episode 21 "Holding On"
A college student (Skylar Astin) is admitted with dizziness and nosebleeds but the team soon discovers that he hears his dead brother's voice, and they must try to decide which of his symptoms are psychological in nature. Meanwhile, House and Wilson deal with the fact that the cancer treatment failed; Wilson decides to stop further treatment and die with dignity, while House's pranks inadvertently violate his court probation, which leaves him inevitably facing incarceration well past Wilson's final months.

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