References/Resources: [ Ссылка ]
In this advanced-level video on DNA replication elongation, we discuss in-depth, the replisome movement on the DNA template during the process of DNA replication. We discuss the dynamics of the replication fork. Specifically, we see what is the trombone model of elongation. What is a lagging strand, what is a leading strand, and how are they continuously or discontinuously made? More specifically, we also see why is the Trombone model false? Finally, we discuss the Okazaki Fragment Maturation and dive into the process of joining Okazaki Fragments.
Jump to your favorite section:
00:00 Outline
00:33 Replisome
01:49 Trombone Model
08:10 Trombone Model is False?
10:23 Okazaki Fragments
12:40 DNA Pol III release
15:15 Joining Okazaki Fragments
17:09 Nick Translation
19:21 Strand Displacement
Patreon Page: [ Ссылка ]
Videos on DNA Replication Initiation in Prokaryotes:
Sliding Clamp: [ Ссылка ]
Primosome Assembly: [ Ссылка ]
Origin Melting: [ Ссылка ]
*Must watch playlists*
All videos on DNA Replication: [ Ссылка ]
All videos on Transcription: [ Ссылка ]
All videos on Translation: [ Ссылка ]
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