The treatment of multiple sclerosis (MS) has advanced rapidly since the 1990s, supplied by a consistent influx of new therapeutics over the years. However, as the shift in treatment approaches have begun to develop in response to these new therapeutics, now, some might suggest that therapeutic innovation has become relatively stagnant.
In a conversation with NeurologyLive, Patricia K. Coyle, MD, professor and interim chair, department of neurology, and, Stony Brook University, noted that one thing in particular strikes her about the state of the MS pipeline: the amount of me-too drugs. She specifically pointed to the need for new mechanisms of action to be identified and for the focus to shift to central nervous system repair.
Coyle discussed what these me-too drugs do bring to the table and why they are limiting, as well as what current research in progressive MS has suggested thus far and what available data has taught the community about the disease.
