Chromosomal Instability (CIN) leads to chromosome mis-segregations, creating different forms of aneuploidy over time, as discussed in this video by Klaske Schukken. Some forms of aneuploid are detrimental, while others are favorable to cell growth. CIN is often studied in vitro, it is rarely studied in vivo, despite its role in both cancer and aging. For more, read the full article here: [ Ссылка ]
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