Alomone Labs human proBDNF-biotin retrograde transport in motor neuron axons.
Quantum-dot conjugated to human proBDNF-Biotin (Cat. # B-256-B) (0.25 µg/ml), was added to the distal side of spinal cord explants grown for few days in microfluidic chamber, followed by axonal live imaging using a spinning disc confocal microscope.
Biotinylated neurotrophins enable:
✓ Receptor internalization kinetics
✓ Retrograde transport
✓ Protein movement across neurons
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