#gout
#highbloodpressure
#hyperuricemia
#endothelialdysfunction
#uricacid
Gout and high blood pressure are related due to high levels of uric acid causing endothelial dysfunction. Uric acid is a waste product that is usually excreted through urine. However, high levels can cause hyperuricemia and uric acid crystals can form in joints, leading to gout.
When uric acid levels are high, it can also lead to endothelial dysfunction. Endothelial cells are the cells that line the inside of blood vessels. When these cells become dysfunctional, they can no longer produce nitric oxide, which is a molecule that helps to dilate blood vessels and improve blood flow. As a result, blood vessels become narrowed and blood pressure increases. In addition to endothelial dysfunction, high levels of uric acid can also cause inflammation of blood vessels, which can further contribute to hypertension.
Studies indicate that uric acid can activate the hormone system that regulates blood pressure, leading to hypertension. Insulin resistance caused by high uric acid levels can also contribute to hypertension by causing the body to produce more insulin, which increases blood pressure.
Gout medications, including diuretics, can raise blood pressure. Gout patients taking diuretics should check their blood pressure regularly to keep it healthy.
Overall, it is important for individuals with gout to manage their uric acid levels and monitor their blood pressure regularly to prevent hypertension and reduce their risk of related health complications.
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Disclaimer:- This information is intended to supplement, not substitute, advice from your healthcare provider or doctor. It does not cover all possible uses, precautions, interactions, or side effects, and may not be appropriate for your specific healthcare needs. Always consult with your doctor or another qualified healthcare provider before modifying or discontinuing any prescribed portion of your healthcare plan or treatment, in order to determine the best course of therapy for you. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.
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