Recent COVID-19 masking guidelines announced by the Centers for Disease Control and Prevention, continue to generate a public conversation.

"The decision about masking needs to be nuanced," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Wearing a mask should be based on the risk of infection, the percentage of the population vaccinated, a person's own immune system, and then the role of vaccine variants with the durability of our immune response."

In this Mayo Clinic Q&A podcast, Dr. Poland discusses masking guidelines in further detail. Also, he offers an update on COVID-19 vaccine research for children, and he shares positive news about the decreasing numbers of COVID-19 cases and deaths.

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For the safety of its patients, staff and visitors, Mayo Clinic has strict masking policies in place. Anyone shown without a mask was recorded prior to COVID-19 or recorded in an area not designated for patient care, where social distancing and other safety protocols were followed.

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Dr. Poland has served as a consultant for Merck & Co. Inc., Medicago Inc., GlaxoSmithKline plc, Sanofi Pasteur, Emergent BioSolutions Inc., Dynavax Technologies Corp., Genentech Inc., Eli Lilly and Co., Janssen Pharmaceuticals Inc., Kentucky BioProcessing Inc. and Genevant Sciences Corp. Honoraria: Elsevier.

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