Presented at IUS 2015, Taipei, Taiwan

Title: Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model

Abstract: Our objective was to use shear wave elastography (SWE) to characterize the mechanical properties of an arterial wall with a simulated calcified plaque in an ex vivo setup. A small porcine aorta was used as a model for a human carotid artery and attached to a fixture while pressurized with a water column. The stiffness of the arterial wall and a simulated plaque were estimated using SWE. The mean arterial wall and plaque shear modulus varied from 42 ± 0 kPa to 100 ± 1 kPa and 81 ± 2 kPa to 174 ± 2 kPa respectively over a pressure range of 20-120 mmHg. The results show the ability of SWE to characterize the mechanical properties of an arterial wall with a simulated plaque and take steps toward an in vivo implementation for quantitative plaque assessment.

Authors: Erik Widman, Elira Maksuti, Carolina Amador Carrascal, Matthew W. Urban, Matilda Larsson

IEEE Xplore - [ Ссылка ]

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