EBUS-TBCNB (EBUS guided cryo-biopsy from mediastinal lymph nodes) has made the life of pathologists and pulmonologists easier. A novel technique, wherein, smaller cryobiopsy probe is entered through a preformed track into the lymph nodes and instead of cytology sample, tissue sampling for HPE and IHC is possible. This was a case of suspected malignancy with unknown primary. EBUS-TBCNB confirmed metastatic carcinoma.
