✅”A review of the safety of cosmetic procedures during pregnancy and lactation” 2017

➡️There are no reported safety data on the use of cosmetic fillers during pregnancy. Adverse events that are associated with the use of fillers in the general population include most commonly injection site reactions and rarely delayed onset foreign body granulomas, nodule formation, vascular compromise, hypersensitivity reactions, and cellulitis. Because of the lack of safety evidence in patients who are pregnant, recommendations on the use of fillers in this population cannot be definitive. The injector should consider the potential risks from inadvertent arterial injection of lidocaine mixed with the filler.

➡️Botulinum toxin type A has both cosmetic and medical applications. Current data suggest but not entirely confirm that the toxin does not attain significant systemic concentrations if correctly injected intramuscularly or intradermally. Furthermore, the size of the toxin molecule makes it unlikely to cross the placental barrier. There are no clinical trials on the effects of cosmetic botulinum toxin use in patients who are pregnant. However, there are a number of case reports in which the toxin has been used for various medical procedures in patients who are pregnant without adverse outcomes to the fetus.

Although some cases demonstrate the general safety of botulinum toxin A, there is still insufficient data to make concrete recommendations on whether cosmetic botulinum toxin procedures should be conducted in women who are pregnant. However, it should be noted that if patients who are pregnant are inadvertently injected with botulinum toxin during the first trimester of pregnancy, efforts should be made by the provider to alleviate patient anxiety because of the current lack of evidence on adverse outcomes on the fetus in published case literature. If patients who are pregnant request a cosmetic botulinum toxin procedure, consent forms should state pregnancy as a contraindication to cosmetic botulinum toxin A treatment.

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