A new way to block protein function is to prevent the translation of mRNA into protein.
An Antisense oligonucleotide therapy is one such approach which blocks the protein formation by inhibiting translation step.
6. Definition:
Antisense oligonucleotides are the molecules made of synthetic genetic material, which interact with the natural genetic material that codes the information for production of proteins.
Oligonucleotides are chemically synthesized using phosphoramidites.
The oligonucleotide chain proceeds in the direction of 3’ to 5’ terminus.
