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HIV strains usually bind to the surface molecule CCR5 in order to enter cells. This mutation prevents CCR5 from appearing on an individual's cells, making them HIV resistant. A number of experimental gene therapy approaches aim to mimic this mutation in AIDS patients.

Dr. Pravin D. Potdar, Former Head of Molecular Medicine & Biology, Jaslok Hospital & Research Centre Mumbai, discusses the mechanism of HIV Virus Infecting CD4 cells and various topics on how cell modification can help in HIV resistance.

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