PBMT LASER TREATMENT FOR POST COVID LUNG PROBLEMS :
Post covid 19 pulmonary fibrosis :-
Pulmonary fibrosis is a lung disease that occurs when lung tissue becomes damaged and scarred. This thickened, stiff tissue makes it more difficult for your lungs to work properly. As pulmonary fibrosis worsens, you become progressively more short of breath.
After the COVID-19 outbreak, increasing number of patients worldwide who have survived COVID-19 continue to battle the symptoms of the illness, long after they have been clinically tested negative for the disease. As we battle through this pandemic, the challenging part is to manage COVID-19 sequelae which may vary from fatigue and body aches to lung fibrosis. Preceding coronavirus epidemics have been accompanied with considerable post-viral fibrosis and physical disabilities.
As the novel coronavirus continues its march across the globe — witness the current surges in the US and many parts of Europe and India — devastating pulmonary fibrosis, the scarring or inflammation of the tissue around the air sacs of the lungs, which leads to fatigue and shortness of breath, is being reported in vast numbers of survivors. One of the complications of COVID-19 pneumonia and ARDS is pulmonary fibrosis [2]. Although there is currently no clinical data on the frequency and mechanism of post-COVID-19 pulmonary fibrosis, it is estimated to be affecting around one-third of the patients hospitalized with SARS-COV-2.
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PBMT is an adjunctive treatment option that has demonstrated significant anti-inflammatory effects in pain management, lymphedema, wound healing, and musculoskeletal injuries. Other terms that fall under the category of PBMT include low-level laser therapy (LLLT), cold laser, and biostimulatory laser therapy. PBMT differs from the lasers used in cosmetic and surgical procedures, which destroy or cut tissue. Instead, PBMT uses non-ionizing, non-thermal light sources in the visible and infrared spectra (600–1200 nm), which in turn, reduce inflammation and stimulate healing.Light is applied through the skin and targets the damaged or inflamed tissues. Light energy absorbed by intracellular photoreceptors starts a cascade of photochemical intracellular reactions that improve cellular activity and increase the tissue’s healing process. Furthermore, PBMT is cost-effective, non-invasive, and has no reported adverse side effects in over 50 years of human experience. Experimental and animal models of pulmonary disease, ARDS and infection revealed that PBMT has cellular and molecular effects at multiple levels against both cytokine and bradykinin storms. PBMT down regulates pro inflammatory Interleukins (IL-1b levels, IL-6, MIP-2 mRNA expression, etc.), prostaglandins, and TNF-alpha. PBMT also upregulates anti-inflammatory cytokines such as IL10. PBMT decreases pulmonary microvascular leakage, activates macrophages, T cells, and neutrophil influx.The P2X7 receptor (P2X7r) has been identified as a new potential therapeutic target in COVID-19 pathogenesis.17 P2X7r is constitutively expressed in many cells and is a major factor involved in activation of cytokine storm and lung pathology in response to viruses.PBMT suggests that it is a feasible solution for reducing inflammation, cytokine storm and lung pathology, and may be easily applied to a high volume of patients at low cost per patient.
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