ER To GOLGI TRANSPORT, all you need to know!
This video provides brief introduction as to how protein gets transported from Endoplasmic Reticulum to Golgi apparatus.
Secretory protein are exported from the ER through budding of transport vesicles followed by targeting and fusion of these vesicles to cis-nolgi network. These vesicles which arise from ER contain COP II coating protein and this pathway (from ER to Golgi ) is called the anterograde transport.
Some ER resident proteins also escape ER via this process. Golgi recognises these escaped ER resident proteins and send them back to ER in the same way i.e. formation of vesicle followed by targeting and fusion.
COP-I coating protein coat these vesicles and this pathway is called the retrograde transport.
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