In this video Dr. Venkataram Mysore explores the possibility of genes that are the cause of baldness. The doctor states that baldness is a multifactorial condition with both genetic as well as an environmental influence. Focusing on the genetic background, baldness can either be related to the paternal side or the maternal side. There have been several research studies conducted to identify the gene for baldness, however, there are multiple genes, as the doctor states that are the causal agents for baldness. When it comes to genetic testing to identify the genes for baldness, unfortunately this is not yet available. Instead genome mapping can be done to identify these genes. Recently an actress had a double mastectomy, as there were multiple family members who had a particular gene that caused breast cancer and even this actress had the same gene leading to breast cancer and as a consequence, the mastectomy that she underwent.
Such an identification of the gene responsible for a particular disorder is also known as ‘precision medicine’, which is now becoming available to people. The process of precision medicine is to map the genome at a young age to determine the conditions appearing later on in life. This type of mapping is currently unavailable for diseases like baldness, and may become available in a few decades.
In order determine whether a person will become bald, an overall history of the baldness present in the family on the paternal and the maternal side is assessed to determine whether a person will be affected by baldness. Along with the incidence of baldness there are also metabolic syndromes such as diabetes, obesity and blood pressure. These syndromes are another indication or what the doctor calls ‘second marker’ for baldness. There are other risk factors for baldness such as smoking and a stressful lifestyle that could cause baldness. Therefore, we need to take into account all these factors to determine the causes of baldness.
Dr. Venkataram continues to state that there are two tests that are conducted to determine risk of baldness in a patient. The first is called ‘hair scan’ to determine the density of hair in specific areas on the head, the diameter of hair in these areas, and this gives the idea of whether the hair is undergoing miniaturization or not. The second test is called ‘trichoscopy’. This test measures the variability in the diameter of the hair and provides an insight of whether either male or female pattern baldness will occur.
With all this said, these are a few of the ‘rough’ techniques to determine whether a person will be affected by baldness. Precise diagnosis will only happen with precision medicine and genomic mapping, which is quite far off from the present. It is to be observed that an early diagnosis can be done taking into account family history, the presence of metabolic syndromes, risk factors such as smoking and the onset of baldness.
Dr. Venkataram also states that it is alarming to observe that even students in class 10 have approached him with thinning hair. So it is recommended that people need to visit The Venkat Center to be diagnosed for hair loss and to get recommendations for that a proper diet, exercise, lifestyle and treatment if necessary.
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Disclaimer:
These videos by Venkat Center for Skin, ENT & Plastic Surgery are intended to provide unbiased scientific information to patients. The videos are of generic nature and are meant only to provide general information for educational purposes only. They do not serve as a guide for treatment in any individual case. Patients are advised to consult a practicing doctor for specific treatment advice.

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