Welcome to Biology 2416, Genetics. Here we will be covering Chapter 14 - Gene Mutation and DNA Repair. This is a full genetics lecture covering Chapter 14. Concepts covered include: Mutations, Somatic Mutations, Germ-line mutations, Base substitutions, Insertions, Deletions, Expanding nucleotide repeats, transitions, transversions, Fragile-X syndrome, Forward mutation, reverse mutation, missense mutation, nonsense mutation, silent mutation, neutral mutation, Loss-of-function, Gain-of-function, Conditional, Lethal, Mutation rate, Spontaneous mutations, Induced mutations, Strand slippage, unequal crossing over, mispairing, wobble, replication error, chemical changes, induced mutations, radiation, depurination, deamination, mutagen, base analog, alkylating agents, deamination, hydroxylamine, intercalating agent, pyrimidine dimer, thymine-thymine dimer, SOS system, UV, X-ray, proofreading exonuclease activity, mismatch repair, direct repair, base-excision repair, nucleotide-excision repair, and more.
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Textbook: Genetics Essentials, Concepts and Connections. 4th edition. Benjamin A. Pierce Macmillan Learning
