Antivenom made via hyper-immunization of livestocks such as horse remain the main treatment for snakebite envenomation. However, there are several drawbacks associated with its use to treat snakebite victims. These drawbacks includes adverse effects like allergies, hypersensitivity responses, anaphylaxis. These are mainly caused by the victim’s immune system reacting to the animal’s antibodies. Other drawback are: batch variability, poor antibody preparation, complex manufacturing processes, etc.
Alternatives suggested include: human antibodies, recombinant anti-toxin and expression in cells, plant natural/synthetic inhibitor compounds etc.
Research is still needed in this areas to develop safer, and more effective alternatives or improve the current therapies.
#snakebite #snakevenom #antivenom
You can watch the following videos :
1. How to make antivenoms from livestock horse
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2. Clinical implications of toxins from venomous snakes
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Thanks
Dr BENEDICT OFFOR
benedictoffor@gmail.com
