Cinislioglu, A., et al. (2022). Variation of serum PSA levels in COVID-19
Infected male patients with benign prostatic hyperplasia (BPH): A prospective cohort studys. Urology, 159.
PSA (Prostate Specific Antigen):
Single-chain glycoprotein
PSA is synthesized in malignant prostate cells
AND
In benign conditions such as aging, prostatitis
PSA is NOT a cancer-specific protein, but rather an organ-specific protein
HYPOTHESIS: PSA may be elevated (due to ACE2) in COVID
ACE2 receptors found in high levels in lungs, heart, kidneys, liver, and other High expression organs such as the PROSTATE
Results:
Study included 91 patients, mean age 68.1 years.
Participants had a PSA drawn at least 3 months before COVID infection but not More than 6 months.
At the time of COVID diagnosis, another PSA was drawn.
This PSA showed statistically higher PSA levels than pre-COVID
At 3 months post-covid diagnosis, another PSA was drawn
The post-COVID PSA was elevated compared to pre-COVID, but not statistically significant
