Hospitals across England have recorded the biggest rise in admissions in a single day due to coronavirus since June.
It comes as council leaders and mayors in some of England's biggest northern cities - including Leeds, Liverpool, Newcastle and Manchester - where new cases are rising sharply, have written to ministers warning that the current restrictions are not working. They are especially critical of the 10pm rule for pubs, clubs and restaurants.
New cases of the virus in the north of England have continued to rise despite local lockdown restrictions being imposed on millions of people. Cases in the south of England are relatively low in comparison.
The rate of Coronavirus infections in the UK has almost doubled in a week.
Huw Edwards presents BBC News at Ten reporting by Dan Johnson in Manchester, medical editor Fergus Walsh and health correspondent Sophie Hutchinson.
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