Progesterone is a crucial hormone for women at all stages of life. It helps women in menopause but does have some side effects. A small minority of women experience serious progesterone intolerance symptoms. A progesterone metabolite called Allopregnanolone is the main reason some forms of progesterone help with sleep. Allopregnanolone may be a problem for some women with a history of premenstrual dysphoric disorder (PMDD).
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